Vol. 1, Issue 4 (2016)
Leucas cephalotes (Spreng): Photochemical investigation and antimicrobial activity via cylinder-plate method or cup-plate method
Author(s): Davinder Kumar, Virender Kumar, Pankaj Jangra, Sumitra Singh
Abstract: Leucas cephalotes is an annual herb growing widely in India. The Leucas cephalotes (Roth) Spreng whole herb contains new Labdane, Nor Labdane & Abietone-type, Diterpenes named Leucasdins A (1), B (2), C (3), five sterols and eight flavones. The research summaries phytochemical and pharmacological investigations carried out on Leucas Cephalotes. The ethanolic extract of plant was more effective against V. cholera than the aqueous extract in terms of zone of inhibition. Ethanolic extract was also more effective against C. albicans and A. niger than the aqueous extract of same plant with respective strains. Minimum inhibitory concentration was also tested against the selected strains of micro-organisms. Ethanolic extract showed MIC at 250 μg/ml against S. aureus, E. coli and V. cholera while against C. albicans and A. niger the MIC was found to be 500 μg/ml. Aqueous extract showed MIC at the dose leveling 500 μg/ml for all the test microbial strains. The ethanolic extract of the plant Leucas cephalotes Spreng. Was more active against all the test strains than the aqueous extract.